Beyond the Surface - Skin Community

Hajheydari, Z., Saeedi, M., Morteza-Semnani, K., & Soltani, A. (2014). Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. The Journal of dermatological treatment, 25(2), 123–129. https://doi.org/10.3109/09546634.2013.768328

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Mazzarello, V., Donadu, M. G., Ferrari, M., Piga, G., Usai, D., Zanetti, S., & Sotgiu, M. A. (2018). Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations. Clinical pharmacology : advances and applications, 10, 175–181. https://doi.org/10.2147/CPAA.S180474

Kaminaka, C., Yamamoto, Y., Sakata, M., Hamamoto, C., Misawa, E., Nabeshima, K., Saito, M., Tanaka, M., Abe, F., & Jinnin, M. (2020). Effects of low-dose Aloe sterol supplementation on skin moisture, collagen score and objective or subjective symptoms: 12-week, double-blind, randomized controlled trial. The Journal of dermatology, 47(9), 998–1006. https://doi.org/10.1111/1346-8138.15428

The study suggests that Ayurvedic formulations (including Aloe vera, turmeric), especially the combination of oral tablets and topical cream, can be effective in treating acne vulgaris with minimal side effects. "The results were statistically analyzed and indicated that combination of use of internal and external preparation showed better efficacy as compared to the use of oral formulation alone. " Lalla, J K et al. “Clinical trials of ayurvedic formulations in the treatment of acne vulgaris.” Journal of ethnopharmacology vol. 78,1 (2001): 99-102. doi:10.1016/s0378-8741(01)00323-3